SITAGEN

SPECIFICATION

50mg

Generics

Sitagliptin

About

It is indicated as: - Initial therapy in patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise do not provide adequate glycemic control. As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus

Indication

• Diabetes

Dosage

According to HBA 1c level

Side Effects

 Vomiting • Stomach ache (abdominal pain) • Muscle cramps • A general feeling of not being well with severe tiredness • Difficulty in breathing • Reduced body temperature and heartbeat .

Drug Interactions

Digoxin , Furosemide , Nifedipine , thyroid products, estrogens, oral contraceptives calcium channel blocking drugs, and isoniazid.

When not to Use

 The Sitagliptin is contraindicated in:- Patients with type 1 diabetes. -Patients with known hypersensitivity to Sitagliptin or any other component of the product. - Acute or chronic metabolic acidosis , including ketoacidosis, with or without coma.

Precaution

Sitagliptin are known to be substantially excreted by the kidney. serum creatinine concentrations should be determined regularly.