Description
Description
SPECIFICATION
5Ml
GENERIC
Moxifloxacin HCl
About
Moxifloxacin has in vitro activity against a wide range of Gram-positive and Gram-negative microorganisms. The bactericidal action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV required for bacterial DNA replication, transcription, repair, and recombination. It appears that the C8-methoxy moiety contributes to enhanced activity and lower selection of resistant mutants of Gram-positive bacteria compared to the C8-H moiety. The presence of the bulky bicycloamine substituent at the C 7 position prevents active efflux, associated with the NorA or pmrA genes seen in certain Gram-positive bacteria..
Indication
Moxifloxacin eye drops are used for the treatment of infections of the eye (conjunctivitis) when caused by bacteria.
Side Effects
Common: may affect up to 1 in 10 people Effects in the eye: eye pain, eye irritation, dry eye, itchy eye, redness of the eye General side effects: bad taste . Uncommon: may affect up to 1 in 100 people Effects in the eye: corneal disorder, eye surface inflammation or scarring, broken blood vessel in eye, inflammation or infection of the conjunctiva, abnormal eye sensation, blurred or reduced vision, eye swelling, eyelid abnormality, itching, redness or swelling. General side effects: headache, vomiting, decreased iron in blood, abnormal liver blood tests, pain, throat irritation, abnormal skin sensation, nose discomfort, feeling of a lump in the throat.
Drug Interactions
Ask your doctor or Pharmacist for any drug interactions.
When not to Use
Do not use Moxifloxacin If you are allergic to moxifloxacin, to other quinolones (a certain type of antibiotic), or any of the other ingredients of this medicine.
Precaution
Talk to your doctor or your pharmacist before using Moxifloxacin: If you experience an allergic reaction to Moxifloxacin. Allergic reactions occur uncommonly and serious reactions occur rarely .