NOVOMIX 30

SPECIFICATION

100IU/ML

Generics

Insulin Aspart , Protamine Insulin Aspart

About

The blood glucose lowering effect of insulin aspart is due to the facilitated uptake of glucose following binding of insulin to receptors on muscle and fat cells and to the simultaneous inhibition of glucose output from the liver.NovoMix 30 is a biphasic insulin, which contains 30% soluble insulin aspart. This has a rapid onset of action, thus allowing it to be given closer to a meal (within zero to 10 minutes of the meal) when compared to soluble human insulin. The crystalline phase (70%) consists of protamine-crystallised insulin aspart, which has an activity profile similar to that of human NPH insulin.When NovoMix 30 is injected subcutaneously, the onset of action will occur within 10 to 20 minutes of injection. The maximum effect is exerted between 1 and 4 hours after injection

Indication

NovoMix 30 FlexPen is used to treat diabetes mellitus .

Dosage

According to HBA 1c level

Side Effects

The most common side effect when using insulin is low blood sugar levels (a hypo). • Mild to moderate Other effects: • pain, redness, hives, bruising, swelling or itching at the injection site.Usually these symptoms disappear within a few weeks during continued use. If you have serious or continuing reactions, you may need to stop using NovoRapid® and use another insulin.• a depression or thickening of the skin around the injection site (lipodystrophy).• lumps under your skin (cutaneous amyloidosis).• when you first start your insulin treatment you may get visual problems or swollen hands and feet.

Drug Interactions

Other medicines for the treatment of diabetes , Monoamine oxidase inhibitors (MAOI) (used to treat depression) , Beta-blockers (used to treat high blood pressure) , Angiotensin converting enzyme (ACE) inhibitors (used to treat certain heart conditions or high blood pressure) , Salicylates (used to relieve pain and lower fever) , Anabolic steroids (such as testosterone) , Sulfonamides (used to treat infections) , Oral contraceptives (birth control pills) , Thiazides (used to treat high blood pressure or excessive fluid retention) , Glucocorticoids (such as ‘cortisone’ used to treat inflammation) , Thyroid hormones (used to treat thyroid gland disorders), Sympathomimetics (such as epinephrine [adrenaline], or salbutamol, terbutaline used to treat asthma) , Octreotide and lanreotide.

When not to Use

Insulin Glargine must not be used in patients hypersensitive to insulin glargine or any of its excipients.

Precaution

 with any insulin therapy, injection site reactions may occur and include pain, redness, hives, inflammation, bruising, swelling and itching. Continuous rotation of the injection site within a given area reduces the risk of developing these reactions. Reactions usually resolve in a few days to a few weeks. On rare occasions, injection site reactions may require discontinuation of Insulin Aspart.