DIOVAN

SPECIFICATION

80Mg & 160mg

Generics

Valsartan

About

Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin II synthesis.

Indication

Valsartan is indicated for the treatment of the following conditions: • Hypertension. • Heart failure (NYHA class II-IV) in patients receiving usual therapy (e.g. diuretics, digitalis) who are intolerant to ACE inhibitors. • To improve survival following myocardial infarction in clinically stable patients with clinical or radiological evidence of left ventricular failure and/or with left ventricular systolic dysfunction .

Side Effects

Common : Viral infections, neutropenia, hyperkalemia, dizziness, postural dizziness, vertigo, hypotension, orthostatic hypotension, renal failure and impairment.Uncommon : Upper respiratory tract infection, pharyngitis, sinusitis, insomnia, decreased libido, syncope, vertigo, cardiac failure, hypotension, cough, diarrhea, abdominal pain, back pain, fatigue, asthenia, headache and oedema. Rare : Dizziness.

Drug Interactions

Trimethoprim , Diuretic agents , other medicines to reduce your blood pressure , steroids , medicines to treat cancer , painkillers , drugs for treatment of infections, including fungal infections , arthritis medicines , resins used for high cholesterol, such as colestyramine

When not to Use

Do not take losartan potassium if you are allergic to any of the ingredients in in the list.

Precaution

Patients with primary hyperaldosteronism should not be treated with valsartan as their renin-angiotensin system is not activated.