LEFLOX

SPECIFICATION

250mg , 500mg & 750mg

Generics

Levofloxacin

About

Levofloxacin is a synthetic broad spectrum anti-bacterial agent. Chemically it is a chiral fluorinated carboxyquinolone. It acts by inhibiting DNA-gyrase. It is bactericidal and has activity against many gram +ve, gram –ve and Anaerobic bacteria.

Indication

It is used to treat •Acute & Chronic Sinusitis • Community acquired pneumonia • Complicated Skin & Soft tissue Infections • Acute Pyelonephritis • Acute & Chronic Bronchitis • Nosocomial pneumonia • Complicated & Uncomplicated UTI • Typhoid & paratyphoid fever.

Side Effects

Itching and rash. Nausea, diarrhoea, loss of appetite, abdominal pain, dyspepsia, Headache, vertigo, dizziness, sleeping problems, paraesthesia e.g. like tingling in the hands, restlessness, anxiety, and confusions, drop of blood pressure, tendon pain, tendon rupture (Achilles Tendon).

Drug Interactions

Concurrent Antacids, Sucralfate, Metal Cations, Multivitamins , NSAID’s.

When not to Use

Levofloxacin is contraindicated in cases of hypersensitivity to the active ingredient or any other quinolone.

Precaution

Serious and occasionally hypersensitivity and/or anaphylactic reactions have been reported in patients receiving therapy with quinolone, including Levofloxacin and should be discontinued immediately.