JENTINMET

SPECIFICATION

50/500mg & 50/1000mg

Generics

Sitagliptin + Metformin

About

It is indicated as: - Initial therapy in patients with type 2 diabetes mellitus to improve glycemic control when diet and exercise do not provide adequate glycemic control. As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus inadequately controlled on Metformin HCl or Sitagliptin alone or in patients already being treated with the combination of Sitagliptin and Metformin HCl.

Indication

• Diabetes

Dosage

According to HBA 1c level

Side Effects

 Vomiting • Stomach ache (abdominal pain) • Muscle cramps • A general feeling of not being well with severe tiredness • Difficulty in breathing • Reduced body temperature and heartbeat .

Drug Interactions

Digoxin , Furosemide , Nifedipine , thyroid products, estrogens, oral contraceptives calcium channel blocking drugs, and isoniazid.

When not to Use

 The combination of Sitagliptin and Metformin HCl is contraindicated in:- Patients with type 1 diabetes. -Patients with known hypersensitivity to Sitagliptin, Metformin HCl or any other component of the product. - Acute or chronic metabolic acidosis , including ketoacidosis, with or without coma.

Precaution

Sitagliptin+Metformin HCl are known to be substantially excreted by the kidney.Metformin HCl-related lactic acidosis increases with the degree of insufficiency of renal function, therefore, serum creatinine concentrations should be determined regularly.