XIGA MET
XIGA MET
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Rs.29.32Estimated delivery: 50 Mins in Lahore. 3-4 Days across Pakistan
Shipping: Standard Delivery Charges Rs.150 for Lahore and may vary for other cities. Free Delivery on order value Rs.5000 and above
Description
Description
SPECIFICATION
5/850mg , 5/1000 mg
Generics
Dapagliflozin + Metformin HCL
About
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.
Indication
- Diabetes
Dosage
According to HBA 1c level
Side Effects
Vomiting • Stomach ache (abdominal pain) • Muscle cramps • A general feeling of not being well with severe tiredness • Difficulty in breathing • Reduced body temperature and heartbeat .
Drug Interactions
ACE inhibitors , Flouroquinolones , SGLT2 inhibitors
When not to Use
History of a serious hypersensitivity reaction to dapagliflozin.Severe renal impairment, end-stage renal disease (ESRD), or patients on dialysis.
Precaution
It causes intravascular volume contraction. Symptomatic hypotension can occur after initiating dapagliflozin particularly in patients with impaired renal function (eGFR less than 60 mL/min/1.73 m2), elderly patients, or patients on loop diuretics. Before initiating dapagliflozin in patients, volume status should be assessed and corrected. Monitor for signs and symptoms of hypotension after initiating therapy.