CORTEC

SPECIFICATION

5mg & 10mg

Generics

Enalapril maleate

About

Enalapril works by widening your blood vessels. This lowers your blood pressure. The medicine usually starts to work within an hour, and the effect lasts for at least 24 hours. Some people will require several weeks of treatment until the best effect on your blood pressure is seen.

Indication

Enalapril used • To treat high blood pressure (hypertension). • To treat heart failure (weakening of heart function). It can lower the need to go to hospital and can help some patients live longer.

Side Effects

 Headache, depression, fainting (syncope), • Change in sense of taste, • Shortness of breath • Diarrhoea, abdominal pain • Tiredness (fatigue), depression, • rash, allergic reactions with swelling of the face, lips, tongue or throat with difficulty in swallowing or breathing • High levels of potassium in the blood, increased levels of creatinine in your blood (both are usually detected by a test).

Drug Interactions

Angiotensin II receptor blocker (ARB) or aliskiren , Potassium supplements (including salt substitutes), potassium-sparing diuretics , trimethoprim and cotrimoxazole , lithium , sacubitril , racecadotril , aspirin , Vildagliptin

When not to Use

Do not take Enalapril if: • You are allergic (hypersensitive) to enalapril maleate or any of the other ingredients of Enalapril or to any other ACE inhibitors similar to Enalapril . • You ever had swelling of your face, lips, mouth, tongue or throat which caused difficulty in swallowing or breathing (angioedema) when the reason why was not known or it was inherited. • You have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren .

Precaution

If hypotension occurs, the patient should be placed in a supine position and if necessary, should receive an intravenous infusion of normal saline. A transient hypotensive response is not a contra-indication to further doses, which can usually be given without difficulty once the blood pressure has increased after volume expansion.