CAPOTEN

SPECIFICATION

25mg & 50mg

Generics

Captopril

About

Captopril belongs to a group of medicines called Angiotensin Converting Enzyme (ACE) inhibitors. ACE inhibitors work by helping to widen your blood vessels, which then make it easier for your heart to pump blood through them.

Indication

Captopril is used to treat high blood pressure (hypertension), congestive heart failure, kidney problems caused by diabetes, and to improve survival after a heart attack.

Dosage

According to HBA 1c level

Side Effects

Neutropenia , agranulocytosis , proteinuria , angioadema , pancreatitis , tachycardia , angina , anorexia , drowsiness , heaadache , paraesthesia , hepatic failure , hypotension , rash , loss of apetite , sleep disorders , dizziness , dry mouth , pruritis , aloepecia , blood dyscrasias.

Drug Interactions

Diuretics (thiazide or loop diuretics ) , Potassium-sparing diuretics (triamterene, amiloride and spironolactone), potassium-containing salt substitutes or potassium supplements , anti-hypertensive agents (e.g. beta-blockers and long-acting calcium channel blockers) , Alpha blocking agents , Lithium , Indomethacin, Ibuprofen , Clonidine , Allopurinol, procainamide, cytostatic or immunosuppressive agents, Probenecid , Tricyclic antidepressants/Antipsychotics , Sympathomimetics , sulphonylurea.

When not to Use

Do not take Captopril : If you are allergic (hypersensitive) to captopril, any of the other ingredients in these tablets or other ACE inhibitors.- If you have ever had a reaction which included swelling of the hands, lips face or tongue where the cause was unknown. - If you have diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren - If you are more than 3 months pregnant. (It is also better to avoid Captopril tablets in early pregnancy

Precaution

Captopril should be used with caution in patients with left ventricular valvular and outflow tract obstruction. As limited experience has been obtained in the treatment of acute hypertensive crises, the use of captopril should be avoided in cases of cardiogenic shock and haemodynamically significant obstruction.