Acdermin Gel

SPECIFICATION

20GM

Generics

Clindamycin Phosphate , Tretinoin

About

Clindamycin is an antibiotic. It limits the growth of bacteria associated with acne and the inflammation caused by these bacteria. Tretinoin normalizes the growth of superficial skin cells and causes normal shedding of the cells that clog the hair follicles in areas with acne. This prevents the build-up of sebum and the formation of early acne lesions (blackheads and whiteheads).

Indication

It is used on the skin to treat acne.

Side Effects

Uncommon: may affect up to 1 in 100 people • Acne, dry skin, redness of the skin, increased sebum production, photosensitivity reaction, itching, rash, scaly rash, scaling of the skin, sunburn • Application site reactions such as burning, inflamed skin, dryness, redness of the skin Rare: may affect up to 1 in 1,000 people • Hypersensitivity • Underactive thyroid gland (symptoms may include fatigue, weakness, weight gain, dry hair, rough pale skin, hair loss, increased sensitivity to cold). • Headache • Eye irritation • Gastroenteritis (inflammation of any part of the gastrointestinal tract), nausea • Inflamed skin, herpes simplex (cold sore), rash macular (small, flat, red spots), skin bleeding, skin burning sensation, loss of skin pigmentation, skin irritation • Application site symptoms such as irritation, swelling, superficial skin damage, discolouration, itching, scaling • Feeling hot, pain

Drug Interactions

Sulphur, salicylic acid, benzoyl peroxide or rescinol , erythromycin or metronidazole, aminoglycosides, other antibiotics or corticosteroids .

When not to Use

Do not use : • If you are pregnant • If you are planning a pregnancy • If you are allergic to clindamycin, tretinoin, or any of the other ingredients of this medicine . • If you are allergic to lincomycin. • If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). • If you have a history of colitis with past antibiotic use which is characterised by prolonged or significant diarrhoea or abdominal cramps.

Precaution

Avoid contact of this medicine with the mouth, eyes, mucous membranes and with abraded or eczematous skin. Be careful when applying to sensitive areas of skin. In case of accidental contact with the eyes, rinse with plenty of lukewarm water.