Betaderm N Oinment

SPECIFICATION

15Gm 1S

Generics

 Betamethasone Valerate, Neomycin Sulphate

About

Betamethasone valerate is an active topical corticosteroid which produces a rapid response in those inflammatory dermatoses that are normally responsive to topical corticosteroid therapy and is often effective in the less responsive conditions such as psoriasis. Neomycin sulfate is a broad-spectrum bactericidal antibiotic effective against the majority of bacteria commonly associated with skin infections.

Indication

Betamethasone valerate is a potent topical corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses.

Side Effects

Local hypersensitivity , Hypothalamic-pituitary adrenal (HPA) axis suppression , Cushingoid features (e.g. moon face, central obesity), delayed weight gain/growth retardation in children, osteoporosis, glaucoma,hyperglycaemia/glucosuria, cataract, hypertension, increased weight/obesity, decreased endogenous cortisol levels .

Drug Interactions

CYP3A4 inhibitors (e.g. ritonavir, itraconazole) , neomycin sulphate.

When not to Use

Betamethasone valerate-neomycin sulphate is contraindicated in children under 2 years of age. Due to the known ototoxic and nephrotoxic potential of neomycin sulphate, the use of betamethasone valerate-neomycin sulphate in large quantities or on large areas for prolonged periods of time is contraindicated in circumstances where significant systemic absorption may occur.

Precaution

Bacterial infection is encouraged by the warm, moist conditions within skin folds or caused by occlusive dressings.

When using occlusive dressings, the skin should be cleansed before a fresh dressing is applied.