OFLOBID

SPECIFICATION

200mg , 400mg

Generics

Ofloxacin

About

Ofloxacin inhibits bacterial DNA replication by inhibiting bacterial topoisomerases, particularly DNA gyrase and topoisomerase IV. It is active after oral administration.

Indication

Sucralfate , corticosteroid , NSAIDs e.g. ibuprofen or diclofenac, or theophylline , glibenclamide , cimetidine , probenecid , methotrexate , warfarin , didanosine , furosemide.

Side Effects

GI upset , Skin reactions , CNS disturbances , reports of hypersensitivity reactions , suicidal thoughts and behaviour, peripheral neuropathy , tendinitis, tendon rupture. Inj : Pain at inj.siite, thrombophlebitis.

Drug Interactions

Sucralfate , corticosteroid , NSAIDs e.g. ibuprofen or diclofenac, or theophylline , glibenclamide , cimetidine , probenecid , methotrexate , warfarin , didanosine , furosemide.

When not to Use

Do not take Ofloxacin: • If you are allergic to ofloxacin or any of the other ingredients of this medicine . Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue. • If you have previously had an allergic reaction to another quinolone antibiotic e.g. ciprofloxacin or norfloxacin. • If you suffer from epilepsy or are at risk of fits .

Precaution

The use of ofloxacin should be avoided in patients who have experienced serious adverse reactions in the past when using quinolone or fluoroquinolone containing products . Treatment of these patients with ofloxacin should only be initiated in the absence of alternative treatment options and after careful benefit/risk assessment .