HYZAAR

SPECIFICATION

50/12.5Mg

Generics

Losartan Potassium , Hydrochlorothiazide

About

It is a combination of an angiotensin II receptor antagonist (losartan) and a diuretic (hydrochlorothiazide). Angiotensin II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Losartan prevents the binding of angiotensin II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Hydrochlorothiazide works by making the kidneys pass more water and salt. This also helps to reduce blood pressure.

Indication

It is used: • Alone or with other blood pressure medicines to lower high blood pressure (hypertension).• To lower the chance of stroke in patients with high blood pressure and a heart problem called left ventricular hypertrophy. It may not help Black patients with this problem.• To slow the worsening of diabetic kidney disease (nephropathy) in patients with type 2 diabetes who have or had high blood pressure.

Side Effects

Low blood sugar (hypoglycaemia) , Loss of appetite, increased uric acid levels or frank gout, increased blood sugar levels, abnormal blood electrolyte levels , Anxiety, nervousness, panic disorder (recurring panic attacks), confusion, depression, abnormal dreams, sleep disorders, sleepiness.

Drug Interactions

Trimethoprim , Diuretic agents , other medicines to reduce your blood pressure , steroids , medicines to treat cancer , painkillers , drugs for treatment of infections, including fungal infections , arthritis medicines , resins used for high cholesterol, such as colestyramine

When not to Use

Do not take losartan potassium if you are allergic to any of the ingredients in in the list.

Precaution

If you are going to have an operation or an anaesthetic, please tell your doctor or dentist that you are taking metoprolol as your heart beat might slow down